Search results for " release of obstruction"

showing 2 items of 2 documents

Congenital reduction in number of nephrons accelerates renal damage, and limits proximal tubular growth response to release of neonatal partial urete…

2012

Aim: to analyze the evolution of the response to persistent partial ureteral obstruction (PUO) and obstruction/release (PUO/Rel) in mice with 50% reduction in the number of nephrons from 21 days of age (time of weaning) to 42 days of age (adulthood). Methods: C57/BL6 wild-type (WT) and mice with oligosyndactylism and 50% reduction of nephron number (Os/+), were subjected to sham operation or PUO in the first 2 days of life. Additional mice underwent release of obstruction at 7 days (PUO-Rel). The study was performed in kidneys harvested at 21 and 42 days. Using histomorphometry, glomerular area (GA) was determined by PAS staining, and fractional proximal tubular (PT) mass and intact glomeru…

Congenital ureteral obstructiontubular damage release of obstruction miceSettore MED/20 - Chirurgia Pediatrica E InfantileUreteral obstruction number of nephrons
researchProduct

URINARY TRACT OBSTRUCTION AND REDUCED NEPHRON NUMBER: ADAPTATION OF NEPHRONS FOLLOWED THROUGH ADULTHOOD IN A MOUSE MODEL

2015

Congenital urinary tract obstruction , NEPHRON NUMBER, MOUSE MODEL , release of obstruction

Congenital urinary tract obstruction NEPHRON NUMBER MOUSE MODEL release of obstruction
researchProduct